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Catalog No.
Product Name
Product Information
Product Citation
  1. Caspase-1/4 inhibitor

    VX-765 is a novel Caspase-1 inhibitor,which is an enzyme that controls the generation of two cytokines, IL-1b and IL-18.
  2. Caspase activator

    PAC-1 is an activator of procaspase-3 induces apoptosis in cancer cells with EC50 of 2.08 μM.
  3. caspase inhibitor

    EP1013 is a broad-spectrum caspase selective inhibitor, used in the research of type 1 diabetes.
  4. caspase inhibitor

    Boc-D-FMK is a cell-permeable, irreversible and broad spectrum caspase inhibitor; inhibits apoptosis stimulated by TNF-α with an IC50 of 39 ?M.
  5. Caspase inhibitor

    Emricasan is a first-in-class caspase inhibitor in clinical trials for the treatment of liver diseases.
  6. Apoptosis Activator

    Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells
  7. Pan Caspase Inhibitor

    Z-VAD-FMK is a cell-permeable, irreversible pan-caspase inhibitor. Inhibits caspase processing and apoptosis induction in tumor cells in vitro (IC50 = 0.0015 - 5.8 mM). Active in vivo.
  8. Caspase-6 inhibitor

    Z-VEID-FMK is the specific recognition sequence for caspase-6/Mch2. Z-VEID-FMK is a synthetic peptide that irreversibly inhibits activity of VEID-dependent caspases (e.g., caspase-6). The inhibitor is designed as a methyl ester to facilitate cell permeability.
  9. Caspase-2 inhibitor

    Z-VDVAD-FMK is a cell-permeable, irreversible inhibitor of caspase-2. Caspase inhibitors play an important role in investigating biological processes.
  10. Caspase-3 inhibitor

    Z-DQMD-FMK is a synthetic peptide that irreversibly inhibits the activity of Caspase-3.
  11. caspase 8 inhibitor

    Z-IETD-FMK is a specific inhibitor of caspase 8.
  12. Apoptosis inducer

    LY573636 is a potent anti-tumor agent, which causes growth arrest and apoptosis of a variety of human solid tumors in vitro and in vivo. LY573636-induced apoptosis occurs by a mitochondrial-targeted mechanism.
  13. Caspase-3 Inhibitor

    Z-DEVD-FMK is a specific, irreversible Caspase-3 inhibitor.
  14. 25-hydroxy Cholesterol is a side-chain substituted oxysterol derived from dietary cholesterol that inhibits the cleavage of sterol regulatory element binding proteins (SREBPs) to suppress endogenous cholesterol synthesis in various cell types
  15. Caspase inhibitor

    Nivocasan is a novel caspase-inhibitor has demonstrated hepatoprotective activity in fibrosis/apoptosis animal models.
  16. Irreversible Cysteine Protease inhibitor

    Z-FA-FMK is an irreversible cysteine protease inhibitor.
  17. Caspase-9 Inhibitor

    Z-LEHD-FMK is a synthetic peptide that irreversibly inhibits caspase-9 and related caspase activity.
  18. Caspase inhibitor

    Q-VD-OPH is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 ( IC50=25nm), caspase-1 (IC50=50nM), caspase-8 (IC50=100nM) and caspase-9 (IC50=430nM).
  19. Caspase inhibitor

    Z-WEHD-FMK is a synthetic peptide that irreversibly inhibits caspase-5 and related caspase activity.
  20. Caspase-3/7 Inhibitor

    Caspase-3/7 Inhibitor I is a potent, cell-permeable, and specific, reversible inhibitor of caspase-3 (Ki = 60 nM) and caspase-7 (Ki = 170 nM).
  21. Fluorogenic caspase substrate

    Ac-LEHD-AFC, fluorogenic caspase substrate. Analog of the caspase-9 substrate, LEHD-AFC.
  22. Caspase-3 inhibitor

    AZ 10417808, selective non-peptide inhibitor of caspase-3 (Ki = 247 nM); displays > 40-fold selectivity over caspases 1, 2, 6, 7 and 8 (Ki > 10 uM).
  23. Caspase-3 inhibitor

    Ivachtin is a potent, cell-permeable, reversible, non-competitive inhibitor of Caspase-3 (IC50 = 23 nM).
  24. Caspase-3 activator

    PETCM is an activator of caspase-3 and a stimulator of apoptosome formation in HeLa cell cytosols.
  25. Fluorogenic caspase substrate

    Ac-LEHD-AFC is a fluorogenic substrate for caspase-4, caspase-5, and caspase-9.
  26. Caspase inhibitor

    BOC-D-FMK is a Novel inhibitor of Caspase-3.
  27. Caspase Inhibitor

    Ac-DEVD-CHO is an aldehyde peptide and a CPP32/Apopain Inhibitor.
  28. Caspase-1 inhibitor

    Z-YVAD-FMK is a potent cell-permeable and irreversible inhibitor of caspase-1.
  29. Caspase inhibitor

    Z-VAD(OH)-FMK is an irreversible tripeptide inhibitor of all caspases.
  30. Cysteine protease inhibitor

    Z-FA-FMK is an irreversible inhibitor of cysteine protease
  31. pan-caspase inhibitor

    MX1013 is a dipeptide pan-caspase inhibitor that inhibits caspase-1, caspase-3, and caspase-6, 7, 8, and 9.
  32. caspase inhibitor

    Biotin-VAD-FMK is a cell permeable, irreversible biotin-labeled caspase inhibitor, used to identify active caspases in cell lysates.
  33. Apaf-1 inhibitor

    ZYZ-488 is a competitive apoptotic protease activating factor-1 (Apaf-1) inhibitor, which inhibits the activation of binding protein procaspase-9 and procaspase-3.
  34. caspase 1 inhibitor

    ML132 (NCGC 00185682) is a potent and selective caspase 1 inhibitor with an IC50 of 0.316 nM.

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