R1530

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Chk2, KDR, FGFR, Aurora A & Cdk2 inhibitor

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Catalog No. A13111

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
R1530 5mg A13111-5

Regular Price: $60.00

Special Price: $51.00

R1530 10mg A13111-10

Regular Price: $100.00

Special Price: $85.00

R1530 25mg A13111-25

Regular Price: $200.00

Special Price: $170.00

R1530 50mg A13111-50

Regular Price: $320.00

Special Price: $272.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

R1530 is a pyrazolobenzodiazepine small molecule with potential antiangiogenesis and antineoplastic activities. R1530 is also a mitosis-angiogenesis inhibitor (MAI) that inhibits multiple receptor tyrosine kinases involved in angiogenesis, such as vascular endothelial growth factor receptor (VEGFR)-1, -2, -3, platelet-derived growth factor receptor (PDGFR) beta? FMS-like tyrosine kinase (Flt)-3, and fibroblast growth factor receptor (FGFR) -1, -2.

R1530

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Chemical Information

Catalog Num A13111
Actions Inhibitor
M. Wt 356.78
Formula C18H14ClFN4O
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 882531-87-5
Synonyms R-1530, R 1530
SMILES code CC1=C2C(=NC3=CC(=C(C=C3C(=N2)C4=CC=CC=C4Cl)F)OC)NN1
Chemical Name 5-(2-chlorophenyl)-7-fluoro-8-methoxy-3-methyl-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepine

Biological Activity

Description
R1530 is a pyrazolobenzodiazepine small molecule with potential antiangiogenesis and antineoplastic activities. R1530 is also a mitosis-angiogenesis inhibitor (MAI) that inhibits multiple receptor tyrosine kinases involved in angiogenesis, such as vascular endothelial growth factor receptor (VEGFR)-1, -2, -3, platelet-derived growth factor receptor (PDGFR) beta? FMS-like tyrosine kinase (Flt)-3, and fibroblast growth factor receptor (FGFR) -1, -2.

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