Raltegravir (MK-0518)

Catalog No.: A10775
HIV-1 integrase inhibitor
Raltegravir (MK-0518) targets integrase, an HIV enzyme that integrates the viral genetic material into human chromosomes, a critical step in the pathogenesis of HIV.
Grouped product items
Product Name Price Stock Qty
Raltegravir 5mg
$45.00
In stock
Raltegravir 10mg
$65.00
In stock
Raltegravir 50mg
$160.00
In stock
Raltegravir 100mg
$255.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Raltegravir (MK-0518) has been cited by 2 publications
  • Michal S Barski, .et al. , Nat Commun, 2021, Aug 17;12(1):4996 PMID: 34404793
  • Lea El Khoury, .et al. , PeerJ Preprints, 2019, 7:e27833v1
  • Biological Activity
    Discription Raltegravir (MK-0518) targets integrase, an HIV enzyme that integrates the viral genetic material into human chromosomes, a critical step in the pathogenesis of HIV.
    Product Information
    Catalog Num A10775
    Formula C20H21FN6O5
    Molecular Weight 444.4
    CAS Number 518048-05-0
    SMILES CC1=NN=C(O1)C(=O)NC(C)(C)C2=NC(=C(C(=O)N2C)O)C(=O)NCC3=CC=C(C=C3)F
    Synonyms Isentress, MK0518, MK-0518
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 80 mg/mL (180.01 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+40% PEG 300+2% Tween 80+ddH2O 7 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.5 mL 112.51 mL 225.02 mL
    0.5 mM 4.5 mL 22.5 mL 45 mL
    1 mM 2.25 mL 11.25 mL 22.5 mL
    5 mM 0.45 mL 2.25 mL 4.5 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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