DNA methyltransferase inhibitor

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Catalog No. A13054

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
RG108 25mg A13054-25
RG108 50mg A13054-50
RG108 100mg A13054-100
RG108 10mM * 1mL in DMSO A13054-10mM-D

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

RG108 is a non-nucleoside inhibitor of DNA methyltransferase with IC50 of 115 nM.


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Chemical Information

Catalog Num A13054
Actions Inhibitor
M. Wt 334.33
Formula C19H14N2O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 48208-26-0
Synonyms RG 108, RG-108
SMILES code C1=CC=C2C(=C1)C(=O)N(C2=O)[[email protected]@H](CC3=CNC4=CC=CC=C43)C(=O)O
Chemical Name (S)-3-(Indol-3-yl)-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propanoic acid

Biological Activity

RG108 is a non-nucleoside inhibitor of DNA methyltransferase with IC50 of 115 nM.
DNA methyltransferase (Cell-free assay)
115 nM


Solubility (25°C)* In vitro DMSO 67 mg/mL (200.4 mM)
Water <1 mg/mL (<1 mM)
Ethanol 67 mg/mL (200.4 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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