SB 415286

Catalog No.: A11061
GSK-3 inhibitor
SB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3α with an IC50 value of 78 nM (similar potency for GSK3β) and a Ki value of 31 nM.
Grouped product items
Product Name Price Stock Qty
SB 415286 10mg
$90.00
In stock
SB 415286 25mg
$180.00
In stock
SB 415286 50mg
$320.00
In stock
SB 415286 100mg
$580.00
In stock
SB 415286 10mM * 1mL in DMSO
$91.00
In stock
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Biological Activity
Discription SB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3α with an IC50 value of 78 nM (similar potency for GSK3β) and a Ki value of 31 nM.
Targets
Target Value
Product Information
Catalog Num A11061
Formula C16H10ClN3O5
Molecular Weight 359.7
CAS Number 264218-23-7
SMILES C1=CC=C(C(=C1)C2=C(C(=O)NC2=O)NC3=CC(=C(C=C3)O)Cl)[N+](=O)[O-]
Synonyms SB-415286, SB415286
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 63 mg/mL (175.13 mM)
Water Insoluble
Ethanol 63 mg/mL (175.13 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.8 mL 139 mL 278.01 mL
0.5 mM 5.56 mL 27.8 mL 55.6 mL
1 mM 2.78 mL 13.9 mL 27.8 mL
5 mM 0.56 mL 2.78 mL 5.56 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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