SMER3 is a selective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCFMet30) in vitro and in vivo. Induces the expression of MET genes; blocks cell proliferation.
SMER3 is a selective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCFMet30) in vitro and in vivo. Induces the expression of MET genes; blocks cell proliferation.
Cell Research
Cell Line
Type
Value
Description
References
Product Information
Catalog Num
A13253
Formula
C11H4N4O2
Molecular Weight
224.18
CAS Number
67200-34-4
SMILES
C1=CC=C2C(=C1)C3=NC4=NON=C4N=C3C2=O
Synonyms
SMER 3, SMER3
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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