TH588

MTH1 inhibitor

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Catalog No. A15537

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
TH588 10mg A15537-10
$100.00
TH588 25mg A15537-25
$200.00
TH588 50mg A15537-50
$350.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

TH588 is first-in-class nudix hydrolase family inhibitor that potently and selectively engage and inhibit the MTH1(IC50= 5 nM) in cells,

TH588

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Chemical Information

Catalog Num A15537
Actions Inhibitor
M. Wt 295.17
Formula C13H12Cl2N4
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1609960-31-7
Synonyms TH-588, TH 588
SMILES code C1CC1NC2=NC(=NC(=C2)C3=C(C(=CC=C3)Cl)Cl)N
Chemical Name (Z)-N-(6-(2,3-dichlorophenyl)-2-imino-2,3-dihydropyrimidin-4(1H)-ylidene)cyclopropanamine

Biological Activity

Description
TH588 is first-in-class nudix hydrolase family inhibitor that potently and selectively engage and inhibit the MTH1(IC50= 5 nM) in cells,
Targets
MTH1 (NUDT1)
5 nM

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