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DNA Damage
MTH1

MTH1

Catalog No.

Product Name

Application

Product Information

Product Citation

A14291

(S)-crizotinib

MTH1 (NUDT1) inhibitor

(S)-crizotinib, the (S)-enantiomer of crizotinib, is a potent MTH1 (NUDT1) inhibitor with IC50 of 72 nM.

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A15536

TH287

MTH1 inhibitor

TH287 is a potent inhibitor of MTH1 (NUDT1) with an IC50 value of 0.8 nM, less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16,

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A15537

TH588

MTH1 inhibitor

TH588 is first-in-class nudix hydrolase family inhibitor that potently and selectively engage and inhibit the MTH1(IC50= 5 nM) in cells,

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