TIC10 isomer

AKT inhibitor‎

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Catalog No. A12720

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
TIC10 isomer 5mg A12720-5
$60.00
TIC10 isomer 10mg A12720-10
$100.00
TIC10 isomer 25mg A12720-25
$200.00
TIC10 isomer 10mM * 1mL in DMSO A12720-10mM-D
$105.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics.

TIC10 isomer

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Chemical Information

Catalog Num A12720
Actions Inhibitor
M. Wt 386.5
Formula C24H26N4O
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 41276-02-2
Synonyms TIC 10, TIC-10
SMILES code CC1=CC=CC=C1CN2C3=C(CN(CC3)CC4=CC=CC=C4)C(=O)N5C2=NCC5
Chemical Name 7-benzyl-10-(2-methylbenzyl)-2,3,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[4,3-d]pyrimidin-5(10H)-one

Biological Activity

Description
TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics.
Targets
Akt ERK

Solubility

Solubility (25°C)* In vitro DMSO 11 mg/mL (28.46 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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