Vandetanib (ZD6474) ON SALE VEGFR inhibitor

0 Customer Reviews
Catalog No. A10963

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Vandetanib 25mg A10963-25

Regular Price: $60.00

Special Price: $51.00

Vandetanib 50mg A10963-50

Regular Price: $100.00

Special Price: $85.00

Vandetanib 100mg A10963-100

Regular Price: $200.00

Special Price: $170.00

Vandetanib 500mg A10963-500

Regular Price: $600.00

Special Price: $510.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Vandetanib (Zactima) is a VEGFR and EGFR antagonist and a tyrosine kinase inhibitor with IC50 of 60, 90, 40 nM for HUVEC proliferation, PC-9 cells and tyrosine kinase activity, respectively.

Vandetanib (ZD6474)

Double click on above image to view full picture

Zoom Out
Zoom In

More Views

Publications citing Adooq Products

Chemical Information

Catalog Num A10963
Actions Inhibitor
M. Wt 475.4
Formula C22H24BrFN4O2
Solubility DMSO>4mg/mL Water<1mg/mL Ethanol>3mg/mL
Purity >98%
Storage at -20°C 2 years
CAS No. 443913-73-3
Synonyms ZD6474
SMILES code CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC
Chemical Name N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine

Biological Activity

Description
Vandetanib (Zactima) is a VEGFR and EGFR antagonist and a tyrosine kinase inhibitor with IC50 of 60, 90, 40 nM for HUVEC proliferation, PC-9 cells and tyrosine kinase activity, respectively.
Targets
VEGFR2 (Cell-free assay)
40 nM

Solubility

Solubility (25°C)* In vitro DMSO 4 mg/mL (8.41 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

View Related Products By Research Topics

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.


Keywords:buy Vandetanib (ZD6474) | Vandetanib (ZD6474) Supplier | purchase Vandetanib (ZD6474) | Vandetanib (ZD6474) cost | Vandetanib (ZD6474) manufacturer | order Vandetanib (ZD6474) | Vandetanib (ZD6474) distributor | buy 443913-73-3| 443913-73-3 Supplier | purchase 443913-73-3 | 443913-73-3 cost | 443913-73-3 manufacturer | order 443913-73-3 | 443913-73-3 distributor