Vandetanib HCl

Catalog No.: A15271

VEGFR inhibitor

Vandetanib HCl

Vandetanib HCl Chemical Structure

CAS NO. 524722-52-9

Vandetanib is a potent inhibitor of VEGFR2 with IC50 of 40 nM.

Availability: In stock

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50 mg

Regular Price: $60.00

Special Price $48.00

100 mg

Regular Price: $100.00

Special Price $80.00

200 mg

Regular Price: $160.00

Special Price $128.00

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Biological Activity

Vandetanib is a potent inhibitor of VEGFR2 with IC50 of 40 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.54 mL 97.69 mL 195.39 mL
0.5 mM 3.91 mL 19.54 mL 39.08 mL
1 mM 1.95 mL 9.77 mL 19.54 mL
5 mM 0.39 mL 1.95 mL 3.91 mL

*The above data is based on the productmolecular weight 511.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15271
Actions Inhibitor
CAS No. 524722-52-9
Formula C22H25BrClFN4O2
M. Wt 511.81
Purity >98%
Synonyms Zactima hydrochloride, ZD6474 hydrochloride, ZD-6474 hydrochloride, ZD 6474 hydrochloride
SMILES CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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