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Vandetanib is a potent inhibitor of VEGFR2 with IC50 of 40 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.97 mL | 84.83 mL | 169.67 mL |
| 0.5 mM | 3.39 mL | 16.97 mL | 33.93 mL |
| 1 mM | 1.7 mL | 8.48 mL | 16.97 mL |
| 5 mM | 0.34 mL | 1.7 mL | 3.39 mL |
*The above data is based on the productmolecular weight 589.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Technical Details
| Catalog Num | A15272 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 589.38 |
| Formula | C24H25BrF4N4O4 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 338992-53-3 |
| Synonyms | Zactima trifluoroacetate, ZD6474 trifluoroacetate, ZD-6474 trifluoroacetate, ZD 6474 trifluoroacetate |
| SMILES | CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC.C(=O)(C(F)(F)F)O |
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