VS-5584

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PI3K/mTOR inhibitor

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Catalog No. A12480

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
VS-5584 10mg A12480-10

Regular Price: $120.00

Special Price: $96.00

VS-5584 25mg A12480-25

Regular Price: $250.00

Special Price: $200.00

VS-5584 50mg A12480-50

Regular Price: $400.00

Special Price: $320.00

VS-5584 10mM * 1mL in DMSO A12480-10mM-D

Regular Price: $95.00

Special Price: $76.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

VS-5584 is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.

VS-5584

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Chemical Information

Catalog Num A12480
Actions Inhibitor
M. Wt 354.41
Formula C17H22N8O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1246560-33-7
Synonyms SB2343, VS5584, SB-2343, SB 2343
SMILES code CC1=NC2=C(N=C(N=C2N1C(C)C)N3CCOCC3)C4=CN=C(N=C4)N
Chemical Name N/A

Biological Activity

Description
VS-5584 is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
Targets
PI3Kα PI3Kδ PI3Kγ mTOR PI3Kβ
2.6 nM2.7 nM3.0 nM3.4 nM21 nM

Solubility

Solubility (25°C) * In vitro DMSO 71 mg/mL (200.33 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (8.46 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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