Neflamapimod (VX-745)

Catalog No.: A10983
p38 MAPK inhibitor
VX-745 is a small-molecule inhibitor of MAPK that is reported to be active against several isotypes of p38 MAPK, including p38α, p38βand p38γ .
Grouped product items
Product Name Price Stock Qty
VX-745 5mg
$50.00
In stock
VX-745 10mg
$80.00
In stock
VX-745 50mg
$250.00
In stock
VX-745 100mg
$450.00
In stock
VX-745 10mM * 1mL in DMSO
$120.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Biological Activity
Discription VX-745 is a small-molecule inhibitor of MAPK that is reported to be active against several isotypes of p38 MAPK, including p38α, p38βand p38γ .
Targets
Target Value
Product Information
Catalog Num A10983
Formula C19H9Cl2F2N3OS
Molecular Weight 436.3
CAS Number 209410-46-8
SMILES C1=CC(=C(C(=C1)Cl)C2=C3C=CC(=NN3C=NC2=O)SC4=C(C=C(C=C4)F)F)Cl
Synonyms VX745
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 15 mg/mL (34.38 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.92 mL 114.6 mL 229.2 mL
0.5 mM 4.58 mL 22.92 mL 45.84 mL
1 mM 2.29 mL 11.46 mL 22.92 mL
5 mM 0.46 mL 2.29 mL 4.58 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
Keywords: buy Neflamapimod (VX-745) | Neflamapimod (VX-745) Supplier | purchase Neflamapimod (VX-745) | Neflamapimod (VX-745) cost | Neflamapimod (VX-745) manufacturer | order Neflamapimod (VX-745) | Neflamapimod (VX-745) distributor | buy 209410-46-8 | 209410-46-8 Supplier | purchase 209410-46-8 | 209410-46-8 cost | 209410-46-8 manufacturer | order 209410-46-8 | 209410-46-8 distributor