VX-770 (Ivacaftor)
VX-770 (Ivacaftor) is known as a CFTR potentiator.
Free Delivery on orders over $500
Research use only. We do not sell to patients.
Loading distributor info...
Adooq Products cited in reputable paper
Adooq's VX-770 (Ivacaftor) has been cited by 2 publications
- Daichi Hinata, .et al. , Int J Mol Sci, 2023, Jan 24;24(3):2305 PMID: 36768629
- Okiyoneda T, .et al. , Dev Cell, 2018, Mar 26;44(6):694-708.e7 PMID: 29503157
Biological Activity
| Description | VX-770 (Ivacaftor) is known as a CFTR potentiator. | |||||
|---|---|---|---|---|---|---|
| Targets |
| |||||
| Cell Research |
|
Product Information
| Catalog Num | A10985 |
|---|---|
| Formula | C24H28N2O3 |
| Molecular Weight | 392.5 |
| CAS Number | 873054-44-5 |
| SMILES | CC(C)(C)C1=CC(=C(C=C1NC(=O)C2=CNC3=CC=CC=C3C2=O)O)C(C)(C)C |
| Synonyms | Kalydeco, VX770 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 69 mg/mL (175.8 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.48 mL | 127.39 mL | 254.78 mL |
| 0.5 mM | 5.1 mL | 25.48 mL | 50.96 mL |
| 1 mM | 2.55 mL | 12.74 mL | 25.48 mL |
| 5 mM | 0.51 mL | 2.55 mL | 5.1 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
