XEN445 ON SALE Endothelial lipase(EL) inhibitor

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Catalog No. A13150

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
XEN445 2mg A13150-2

Regular Price: $180.00

Special Price: $153.00

XEN445 5mg A13150-5

Regular Price: $350.00

Special Price: $297.50

XEN445 10mg A13150-10

Regular Price: $600.00

Special Price: $510.00

XEN445 10mM * 1mL in DMSO A13150-10mM-D

Regular Price: $389.00

Special Price: $330.65

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

XEN445 is a potent and selective EL inhibitor(IC50=0.237 uM), that showed good ADME and PK properties, and demonstrated in vivo efficacy in raising plasma HDLc concentrations in mice.

XEN445

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Chemical Information

Catalog Num A13150
Actions Inhibitor
M. Wt 366.33
Formula C18H17F3N2O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1515856-92-4
Synonyms XEN-445, XEN 445
SMILES code C1CN(CC1OCC2=CC=CC=N2)C3=C(C=C(C=C3)C(F)(F)F)C(=O)O
Chemical Name N/A

Biological Activity

Description
XEN445 is a potent and selective EL inhibitor(IC50=0.237 uM), that showed good ADME and PK properties, and demonstrated in vivo efficacy in raising plasma HDLc concentrations in mice.
Targets
Targets
endothelial lipase
0.237 μM

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