XL147 analogue

Catalog No.: A10995
PI3K Inhibitor
XL147 is a potent, selective and orally bioavailable small molecule inhibitor of class I phosphatidylinositol 3 kinase (PI3K) with potential antineoplastic activity.
Grouped product items
Product Name Price Stock Qty
XL147 10mg
$100.00
In stock
XL147 25mg
$200.00
In stock
XL147 50mg
$280.00
In stock
XL147 100mg
$480.00
In stock
Bulk Size
Bulk Discount
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's XL147 analogue has been cited by 1 publications
  • Yushi Hayashida, .et al. , Int J Cancer, 2016, Aug 1;139(3):700-11 PMID: 26989815
  • Biological Activity
    Discription XL147 is a potent, selective and orally bioavailable small molecule inhibitor of class I phosphatidylinositol 3 kinase (PI3K) with potential antineoplastic activity.
    Targets
    Target Value
    Product Information
    Catalog Num A10995
    Formula C21H16N6O2S2
    Molecular Weight 448.5
    CAS Number 956958-53-5
    SMILES CC1=CC=C(C=C1)S(=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=CC5=NSN=C5C=C4
    Synonyms XL-147, SAR245408
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 3 mg/mL (6.68 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 14 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.3 mL 111.48 mL 222.97 mL
    0.5 mM 4.46 mL 22.3 mL 44.59 mL
    1 mM 2.23 mL 11.15 mL 22.3 mL
    5 mM 0.45 mL 2.23 mL 4.46 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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