XL765
Catalog No.: A10997
PI3K inhibitor
Free Delivery on orders over $500
Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Biological Activity
| Description | XL765 is a PI3K/mTOR dual kinase inhibitor and it is more potent compared to an agent that inhibits either PI3K kinase or mTOR kinase alone. | ||
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| Targets |
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Product Information
| Catalog Num | A10997 |
|---|---|
| Formula | C31H29N5O6S |
| Molecular Weight | 599.7 |
| CAS Number | 1349796-36-6 |
| SMILES | CC1=C(C=C(C=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC4=CC=CC=C4N=C3NC5=CC(=CC(=C5)OC)OC)OC |
| Synonyms | XL-765 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 10 mg/mL (16.68 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.68 mL | 83.38 mL | 166.75 mL |
| 0.5 mM | 3.34 mL | 16.68 mL | 33.35 mL |
| 1 mM | 1.67 mL | 8.34 mL | 16.68 mL |
| 5 mM | 0.33 mL | 1.67 mL | 3.34 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
