ZM 39923 HCl

JAK3 inhibitor

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Catalog No. A13509

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
ZM 39923 HCl 10mg A13509-10
$90.00
ZM 39923 HCl 25mg A13509-25
$180.00
ZM 39923 HCl 50mg A13509-50
$300.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

ZM 39923 HCl is an inhibitor of JAK3 (IC50 = 79 nM) that less potently inhibits epidermal growth factor receptor, JAK1, and cyclin-dependent kinase 4 (IC50s = 2.4, 40, and 10 M, respectively)

ZM 39923 HCl

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Chemical Information

Catalog Num A13509
Actions Inhibitor
M. Wt 367.9
Formula C23H25NOHCl
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1021868-92-7
Synonyms JAK3 Inhibitor IV
SMILES code O=C(CCN(CC1=CC=CC=C1)?C(C)?C)?C2=CC3=CC=CC=C3C=C2.Cl
Chemical Name 3-[(1-methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)-1-propanone, monohydrochloride

Biological Activity

Description
ZM 39923 HCl is an inhibitor of JAK3 (IC50 = 79 nM) that less potently inhibits epidermal growth factor receptor, JAK1, and cyclin-dependent kinase 4 (IC50s = 2.4, 40, and 10 M, respectively)
Targets
TGM2 JAK3 EGFR JAK1
10 nM7.1(pIC50)5.6(pIC50)4.4(pIC50)

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