1,3,5-Trihydroxy-4-prenylxanthone is an inhibitor of phosphodiesterase type 5 (PDE5) and the Na+/H+ exchanger, with an IC50 value of 3.0 μM and a minimum inhibitory concentration of 10 μg/mL. It effectively inhibits lipopolysaccharide (LPS)-induced nitric oxide production in RAW264.7 macrophages, showcasing its potential anti-inflammatory properties. This compound is valuable for research applications focused on inflammatory pathways and cellular signaling involving nitric oxide.
1,3,5-Trihydroxy-4-prenylxanthone is an inhibitor of phosphodiesterase type 5 (PDE5) and the Na+/H+ exchanger, with an IC50 value of 3.0 μM and a minimum inhibitory concentration of 10 μg/mL. It effectively inhibits lipopolysaccharide (LPS)-induced nitric oxide production in RAW264.7 macrophages, showcasing its potential anti-inflammatory properties. This compound is valuable for research applications focused on inflammatory pathways and cellular signaling involving nitric oxide.
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