1-Cbz-3-Hydroxyazetidine

Catalog No.: A42860
ADC Linker
1-Cbz-3-Hydroxyazetidine is a non-cleavable ADC linker designed for the synthesis of antibody-drug conjugates (ADCs). Its structural features facilitate stability and efficacy in targeted drug delivery systems. Additionally, this compound serves as an alkyl chain-based PROTAC linker, making it valuable in the development of proteolysis-targeting chimeras (PROTACs) for enhanced protein degradation studies.
Grouped product items
Size Price Stock Qty
50g
$30.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description1-Cbz-3-Hydroxyazetidine is a non-cleavable ADC linker designed for the synthesis of antibody-drug conjugates (ADCs). Its structural features facilitate stability and efficacy in targeted drug delivery systems. Additionally, this compound serves as an alkyl chain-based PROTAC linker, making it valuable in the development of proteolysis-targeting chimeras (PROTACs) for enhanced protein degradation studies.
Product Information
Catalog NumA42860
FormulaC11H13NO3
Molecular Weight207.23
CAS Number128117-22-6
SMILESO=C(N1CC(O)C1)OCC2=CC=CC=C2
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2