1-Methyl-2-undecyl-4(1H)-quinolone is a selective and irreversible inhibitor of type B monoamine oxidase (MAO-B). It exhibits potent inhibition with IC50 and Ki values of 15.3 μM and 9.91 μM, respectively, without affecting type A monoamine oxidase (MAO-A) activity. This quinolone alkaloid, derived from the fresh leaves and fruits of Evodia rutaecarpa, is valuable in research focused on neurological disorders and the modulation of neurotransmitter levels.
1-Methyl-2-undecyl-4(1H)-quinolone is a selective and irreversible inhibitor of type B monoamine oxidase (MAO-B). It exhibits potent inhibition with IC50 and Ki values of 15.3 μM and 9.91 μM, respectively, without affecting type A monoamine oxidase (MAO-A) activity. This quinolone alkaloid, derived from the fresh leaves and fruits of Evodia rutaecarpa, is valuable in research focused on neurological disorders and the modulation of neurotransmitter levels.
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