1-Piperazinehexanoic acid-thalidomide

Catalog No.: A80055
E3 Ligase Ligand-Linker Conjugates
1-Piperazinehexanoic acid-thalidomide functions as an E3 ligase ligand-linker conjugate, essential for the synthesis of complete JMV7048. This compound plays a critical role in the development of targeted protein degradation strategies, facilitating research into therapeutic applications in oncology and other diseases. Its structural properties enable efficient conjugation, advancing the understanding of E3 ligase modulation in biological systems.
Grouped product items
Size Price Stock Qty
5mg
$300.00
In stock
10mg
$490.00
In stock
25mg
$1,030.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description1-Piperazinehexanoic acid-thalidomide functions as an E3 ligase ligand-linker conjugate, essential for the synthesis of complete JMV7048. This compound plays a critical role in the development of targeted protein degradation strategies, facilitating research into therapeutic applications in oncology and other diseases. Its structural properties enable efficient conjugation, advancing the understanding of E3 ligase modulation in biological systems.
Product Information
Catalog NumA80055
FormulaC23H28N4O6
Molecular Weight456.49
CAS Number2819682-33-0
SMILESO=C(O)CCCCCN1CCN(C2=CC=C(C(N(C3CCC(NC3=O)=O)C4=O)=O)C4=C2)CC1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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