Fig. 1 · Structure

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10-Methoxycamptothecin

10-methoxycamptothecin, the major alkaloids of the parent plant.

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Biological Activity

Cellular Effect

Cell Line Activity Value Description Reference
A549 IC50 0.04 μM Antitumor activity against human A549/ATCC cells by SRB method [PMID: 19541483]
HT-29 IC50 0.076 μM Antitumor activity against human HT-29 cells by SRB method [PMID: 19541483]

Specifications

Manufacturer Adooq Bioscience
CAS Number 19685-10-0
Formula C21H18N2O5
Molecular Weight 378.38
SMILES
CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)OC)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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