10-Nitrolinoleic acid

Catalog No.: A40016
PPARγ Agonist
10-Nitrolinoleic acid is a potent agonist of peroxisome proliferator-activated receptor γ (PPARγ). It demonstrates the ability to compete with [3H]Rosiglitazone for binding to PPARγ, achieving an IC50 value of 0.22 μM. This compound is valuable for research focused on metabolic regulation and the modulation of insulin sensitivity, making it relevant in studies of obesity and type 2 diabetes.
Grouped product items
Size Price Stock Qty
100µg
$140.00
In stock
500µg
$605.00
In stock
1mg
$1,065.00
In stock
Bulk Size
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description10-Nitrolinoleic acid is a potent agonist of peroxisome proliferator-activated receptor γ (PPARγ). It demonstrates the ability to compete with [3H]Rosiglitazone for binding to PPARγ, achieving an IC50 value of 0.22 μM. This compound is valuable for research focused on metabolic regulation and the modulation of insulin sensitivity, making it relevant in studies of obesity and type 2 diabetes.
Product Information
Catalog NumA40016
FormulaC18H31NO4
Molecular Weight325.44
CAS Number774603-04-2
SMILESCCCCC/C=C\C/C([N+]([O-])=O)=C\CCCCCCCC(O)=O
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