12-Ethyl-9-hydroxycamptothecin is a derivative of camptothecin that functions primarily as a DNA topoisomerase I inhibitor. With an IC50 value of 679 nM, it displays significant biological activity in impairing DNA replication and transcription. This reagent is utilized in research applications focused on cancer therapeutics and the study of cell cycle regulation.
12-Ethyl-9-hydroxycamptothecin is a derivative of camptothecin that functions primarily as a DNA topoisomerase I inhibitor. With an IC50 value of 679 nM, it displays significant biological activity in impairing DNA replication and transcription. This reagent is utilized in research applications focused on cancer therapeutics and the study of cell cycle regulation.
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