14,15-Dehydro Leukotriene B4 is a selective antagonist of the leukotriene B4 (LTB4) receptors BLT1 and BLT2, exhibiting a binding affinity with a Ki value of 27 nM for BLT1 and 473 nM for BLT2. This compound effectively inhibits LTB4-induced lysozyme release from rat polymorphonuclear leukocytes, with an IC50 of 1 µM. It is useful in studies focused on inflammation and immune response modulation.
14,15-Dehydro Leukotriene B4 is a selective antagonist of the leukotriene B4 (LTB4) receptors BLT1 and BLT2, exhibiting a binding affinity with a Ki value of 27 nM for BLT1 and 473 nM for BLT2. This compound effectively inhibits LTB4-induced lysozyme release from rat polymorphonuclear leukocytes, with an IC50 of 1 µM. It is useful in studies focused on inflammation and immune response modulation.
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