1400W Dihydrochloride

Catalog No.: A13583

INOS inhibitor

1400W Dihydrochloride

1400W Dihydrochloride Chemical Structure

CAS NO. 214358-33-5

1400W Dihydrochloride is a slow, tight binding, potent and highly selective inhibitor of inducible nitric oxide synthase (Kd = 7 nM). Selective over nNOS and eNOS (Ki values are 2 and 50 μM respectively). Cell-permeable and active in vivo.

Availability: In stock

Package Price Qty
5 mg
$50.00
10 mg
$80.00
25 mg
$160.00
50 mg
$280.00
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Biological Activity

1400W Dihydrochloride is a slow, tight binding, potent and highly selective inhibitor of inducible nitric oxide synthase (Kd = 7 nM). Selective over nNOS and eNOS (Ki values are 2 and 50 μM respectively). Cell-permeable and active in vivo.
In vitro DMSO 34 mg/mL (135.9 mM)
Water 34 mg/mL (135.9 mM)
Ethanol 34 mg/mL (135.9 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 39.97 mL 199.84 mL 399.68 mL
0.5 mM 7.99 mL 39.97 mL 79.94 mL
1 mM 4 mL 19.98 mL 39.97 mL
5 mM 0.8 mL 4 mL 7.99 mL

*The above data is based on the productmolecular weight 250.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13583
Actions Inhibitor
CAS No. 214358-33-5
Formula C10H15N3 . 2HCl
M. Wt 250.2
Purity >98%
Synonyms 1400 W
SMILES CC(=NCC1=CC(=CC=C1)CN)N.Cl.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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