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1400W Dihydrochloride is a slow, tight binding, potent and highly selective inhibitor of inducible nitric oxide synthase (Kd = 7 nM). Selective over nNOS and eNOS (Ki values are 2 and 50 μM respectively). Cell-permeable and active in vivo.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 39.97 mL | 199.84 mL | 399.68 mL |
| 0.5 mM | 7.99 mL | 39.97 mL | 79.94 mL |
| 1 mM | 4 mL | 19.98 mL | 39.97 mL |
| 5 mM | 0.8 mL | 4 mL | 7.99 mL |
*The above data is based on the productmolecular weight 250.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13583 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 250.2 |
| Formula | C10H15N3 . 2HCl |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 214358-33-5 |
| Synonyms | 1400 W |
| SMILES | CC(=NCC1=CC(=CC=C1)CN)N.Cl.Cl |
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