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Mps1-IN-1 is a highly potent and selectibe Mpsl inhibitor with IC50 of 367 nM; >1000-fold selectivity relative to the 352 member kinase panel with the major exceptions of Alk and Ltk.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.67 mL | 93.34 mL | 186.69 mL |
| 0.5 mM | 3.73 mL | 18.67 mL | 37.34 mL |
| 1 mM | 1.87 mL | 9.33 mL | 18.67 mL |
| 5 mM | 0.37 mL | 1.87 mL | 3.73 mL |
*The above data is based on the productmolecular weight 535.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A11218 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 535.66 |
| Formula | C28H33N5O4S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1125593-20-5 |
| Synonyms | N/A |
| SMILES | OC1CCN(C2=CC(OC)=C(NC3=NC4=C(C=CN4)C(NC5=C(S(=O)(C(C)C)=O)C=CC=C5)=C3)C=C2)CC1 |
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