2,4-Diamino-6-hydroxypyrimidine

Catalog No.: A13500

GTP cyclohydrolase I inhibitor

2,4-Diamino-6-hydroxypyrimidine

2,4-Diamino-6-hydroxypyrimidine Chemical Structure

CAS NO. CAS: 56-06-4

2,4-Diamino-6-hydroxypyrimidine is a specific GTP cyclohydrolase I inhibitor (the rate-limiting enzyme in de novo pterin synthesis), blocks BH4 synthesis and suppresses NO production.

Availability: In stock

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100 mg
$45.00
500 mg
$135.00
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Biological Activity

2,4-Diamino-6-hydroxypyrimidine is a specific GTP cyclohydrolase I inhibitor (the rate-limiting enzyme in de novo pterin synthesis), blocks BH4 synthesis and suppresses NO production.
In vitro DMSO 21 mg/mL (166.5 mM)
Water 5 mg/mL (39.64 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 79.29 mL 396.45 mL 792.9 mL
0.5 mM 15.86 mL 79.29 mL 158.58 mL
1 mM 7.93 mL 39.64 mL 79.29 mL
5 mM 1.59 mL 7.93 mL 15.86 mL

*The above data is based on the productmolecular weight 126.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13500
Actions Inhibitor
CAS No. CAS: 56-06-4
Formula C4H6N4O
M. Wt 126.12
Solubility DMSO
Purity >98%
SMILES O=C1N=C(N)NC(N)=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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