2-Aminopurine is a fluorescent analog of guanosine and adenosine, functioning as a DNA structure probe. Its insertion into oligonucleotides results in significant fluorescence quenching due to stacking interactions with adjacent natural bases. This property makes 2-Aminopurine an invaluable tool for investigating nucleic acid structure and dynamics in various research applications.
2-Aminopurine is a fluorescent analog of guanosine and adenosine, functioning as a DNA structure probe. Its insertion into oligonucleotides results in significant fluorescence quenching due to stacking interactions with adjacent natural bases. This property makes 2-Aminopurine an invaluable tool for investigating nucleic acid structure and dynamics in various research applications.
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