Biological Activity
a-Hydroxyglutaric acid (2-HG) is an a-hydroxy acid. It is normally metabolized to 2-oxoglutarate by D- and L-2-hydroxyglutarate dehydrogenases, and mutations in these enzymes cause 2-hydroxyglutaric aciduria, a neurometabolic disorder.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 52.06 mL | 260.28 mL | 520.56 mL |
0.5 mM | 10.41 mL | 52.06 mL | 104.11 mL |
1 mM | 5.21 mL | 26.03 mL | 52.06 mL |
5 mM | 1.04 mL | 5.21 mL | 10.41 mL |
*The above data is based on the productmolecular weight 192.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A13632 |
---|---|
M. Wt | 192.1 |
Formula | C5H6O52Na |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 40951-21-1 |
Synonyms | 2-HG, 2-Hydroxyglutaric Acid, a-Hydroxyglutaric acid |
SMILES | [O-]C(C(CCC([O-])=O)O)=O.[Na+].[Na+] |
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