2-HG (sodium salt)

Catalog No.: A13632

2-HG (sodium salt)

2-HG (sodium salt) Chemical Structure

CAS NO. 40951-21-1

a-Hydroxyglutaric acid (2-HG) is an a-hydroxy acid. It is normally metabolized to 2-oxoglutarate by D- and L-2-hydroxyglutarate dehydrogenases, and mutations in these enzymes cause 2-hydroxyglutaric aciduria, a neurometabolic disorder.

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100 mg
$95.00
500 mg
$400.00
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Biological Activity

a-Hydroxyglutaric acid (2-HG) is an a-hydroxy acid. It is normally metabolized to 2-oxoglutarate by D- and L-2-hydroxyglutarate dehydrogenases, and mutations in these enzymes cause 2-hydroxyglutaric aciduria, a neurometabolic disorder.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 52.06 mL 260.28 mL 520.56 mL
0.5 mM 10.41 mL 52.06 mL 104.11 mL
1 mM 5.21 mL 26.03 mL 52.06 mL
5 mM 1.04 mL 5.21 mL 10.41 mL

*The above data is based on the productmolecular weight 192.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13632
CAS No. 40951-21-1
Formula C5H6O5.2Na
M. Wt 192.1
Purity >98%
Synonyms 2-HG, 2-Hydroxyglutaric Acid, a-Hydroxyglutaric acid
SMILES [O-]C(C(CCC([O-])=O)O)=O.[Na+].[Na+]
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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