Other inhibitors

Streptozotocin (Streptozocin, Zanosar, STZ)is used in medical research to produce an animal model for Type 1 diabetes, which directly inhibist the O-GlcNAcase activity of the enzyme NCOAT in vitro. Learn More

Azomycin(2-Nitroimidazole) is an antimicrobial antibiotic produced by a strain of Nocardia mesenterica, which is active against aerobic Gram-positive and Gram-negative bacteria. Learn More

Butylscopolamine BR is an orally available bromide salt form of butylscopolamine which is a peripherally acting antimuscarinic, anticholinergic agent. Learn More

Acarbose is an anti-diabetic drug used to treat type 2 diabetes mellitus and, in some countries, prediabetes. Learn More

BTZ043 (BTZ038, BTZ044) inhibits decaprenylphosphoryl-β-d-ribose 2?-epimerase, which is an enzyme which produces the cell wall of the pathogenic bacterium Mycobacterium tuberculosis. Learn More

Caffeic acid is an organic compound that is classified as hydroxycinnamic acid. Learn More

Silibinin (silybin) is the major active constituent of silymarina compound extracted from the seeds of the herb milk thistle. Learn More

Silymarin (Silibinin B) inhibits chemically induced urinary bladder tumor growth and progression possibly by inhibiting cell proliferation and enhancing apoptosis. Learn More

Sclareolide (Norambreinolide) is a sesquiterpene lactone natural product . Learn More

Nitrisinone is a competitive inhibitor that reversibly inhibits 4-Hydroxyphenylpyruvate oxidase (dioxygenase). Learn More

BAPTA is a selective calcium chelator. Learn More

Cytarabine inhibits DNA replication by incorporating into DNA (IC50 = 0.04 μM in L1210 and CEM cell lines). Learn More

7-Aminocephalosporanic acid is the core chemical structure for the synthesis of cephalosporin antibiotics and intermediates. Learn More

Coenzyme Q10 is a component of the mitochondrial transporter chain that behaves as a powerful antioxidant. Displays neuroprotective activity. Learn More

Cyclovirobuxine D (Bebuxine) is an active compound extracted from Buxus microphylla that significantly increases cardiomyocytes viability injured by oxidation or hypoxia. Learn More

Haematoxylin is extracted from the heartwood of the logwood tree.When oxidized it forms haematein, a compound that forms strongly coloured complexes with certain metal ions, the most notable ones being Fe(III) and Al(III) salts. Metal-haematein complexes are used to stain cell nuclei prior to examination under a microscope. Learn More

Isoliquiritigenin is a licorice chalconoid, a type of natural phenols that is currently under experimentation phase testing for use as a cancer treatment as well as an aide for cocaine addiction. Learn More

Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai and has anti-inflammatory effects. Learn More

L-Ascorbyl 6-palmitate (Ascorbyl palmitate) is an ester formed from ascorbic acid and palmitic acid creating a fat-soluble form of vitamin C. Learn More

Flavanone glycoside with neuroprotective and antioxidant properties. Does not inhibit oral carcinogenesis in a rat model unlike other citrus flavanones, but does exert a protective effect against gastritis and gastric lesions. Learn More

Neohesperidin dihydrochalcone (Nhdc) is a flavonoid sweetening agent with potent antioxidant activity. Learn More

Palmatine chloride is a protoberberine alkaloid that is isolated from medicinal herbs like Coptis chinensis Franch. Learn More

Rhein is a substance in the anthraquinone group found in rhubarb species like Rheum undulatum or Rheum palmatum or in Cassia reticulata. Learn More

Rheochrysidin is one of the major components of Da-Cheng-Qi decoction used in the treatment of inflammation. Learn More

Salidroside (Rhodioloside) is a glucoside of tyrosol found in the plant Rhodiola rosea. It is thought to be one of the compounds responsible for the antidepressant and anxiolytic actions of this plant, along with rosavin. Learn More

Sesamin is a lignan isolated from the bark of Fagara plants and from sesame oil. Learn More

Sophocarpine could reverse isoprenaline-induced arrhythmia and inhibit I(Na), I(CaL), and I(Kr) currents. The electrophysiological effects of sophocarpine are similar to those of amiodarone, which might be regarded as a prospective antiarrhythmic agent. Learn More

Chondroitin sulfate is a sulfated glycosaminoglycan (GAG) composed of a chain of alternating sugars. Learn More

LY2608204 is a potent used to treat type 2 diabetes. In a clinical trial, a study was performed to evaluate the safety and tolerability of LY2608204 in patients with type 2 diabetes. Learn More

is a plant hormone in the auxin family and is an ingredient in many commercial horticultural plant rooting products. Learn More

4-Methylumbelliferone is a selective inhibitor of Hyaluronan (HA) synthesis which is thought to function as an inhibitor via the depletion of UDP-glucuronic acid, the common substrate for HA synthesis. Learn More

Aesculin is a glucoside that naturally occurs in the horse chestnut (Aesculus hippocastanum). It is used in a microbiology laboratory to aid in the identification of bacterial species (especially Enterococci and Listeria).

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Aloe emodin is a anthraquinone present in aloe latex, an exudate from the aloe plant. It has a strong stimulant-laxative action.

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Amygdalin is a glycoside initially isolated from the seeds of the tree Prunus dulcis. Amygdalin induces apoptosis through regulation of Bax and Bcl-2 expressions in human DU145 and LNCaP prostate cancer cells.

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Azalomycin-B is a macrolide antibiotic produced by Streptomyces hygroscopicus.

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Berberine hydrochloride was novelly found that it has various beneficial effects on the cardiovascular system and significant anti-inflammatory activities. Berberine can effectively reduce intracellular superoxide levels in LPS-stimulated macrophages. Such a restoration of cellular redox by berberine is mediated by its selective inhibition of gp91phox expression and enhancement of SOD activity.

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Bergenin (Cuscutin) is an isocoumarin isolated from various medicinal plants. Shows mild anti-HIV activity, antihepatotoxic activity and antiulcer activity.

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Bilobalide, a biologically active terpenic trilactone (terpinoid), derived from geranylgeranyl pyrophosphate (GGPP) is an inducer of cytochrome P450 enzymes CYP3A1 and CYP1A2. May contain properties to stop apoptosis activation of the phosphatidylinositol 3-Kinase pathway in SH-SY5Y cells.

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Biochanin A is an antiproliferative and anti-inflammatory agent that inhibits iNOS expression and lipopolysacharide (LPS)-induced nitric oxide production in macrophages. Additionally, Biochanin A displays the ability to block phosphorylation of IκBα and p38 MAPK, which prevents NF-κB activation. Furthermore, Biochanin A has been observed to suppress IL-6, IL-1β, and TNF-α production.

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Chlorogenic acid is an important intermediate in lignin biosynthesis. This compound, long known as an antioxidant, also slows the release of glucose into the bloodstream after a meal.

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Ribitol is a crystalline pentose alcohol formed by the reduction of ribose.

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Myricetin (Cannabiscetin) is a naturally occurring flavonol, a flavonoid found in many grapes, berries, fruits, vegetables, herbs, as well as other plants. Learn More

Nanchangmycin (dianemycin) is a polyether antibiotic with similar structure to dianemycin and is very active against a broad spectrum of harmful nematodes and insects but not for for mammals and plants. Learn More

Naringin (Naringoside) is a flavanone glycoside and is a major flavonoid in grapefruit and gives the grapefruit juice its bitter taste. Learn More

Naringin Dihydrochalcone(Naringin DC) is a new-style sweetening agent and an artificial sweetener derived from naringin. Learn More

Nepafenac is a non-steroidal anti-inflammatory agent. Learn More

Nobiletin is a chemical compound. It is an O-methylated flavone, a flavonoid isolated from citrus peels like in tangerine. Nobiletin was found to have anti-inflammatory and anti-tumor invasion, proliferation, and metastasis in vitro and in vivo. Nobiletin was also found to potentially inhibit cartilage degradation. Learn More

NXY-059 is the disulfonyl derivative of the neuroprotective spin trap pheny lbutynitrone or "PBN" with free radical-trapping properties. It substantially lessens the functional disability resulting from cerebral ischemia in a primate species. Learn More

Oleanolic acid (Caryophyllin) is a naturally occurring triterpenoid, widely distributed in food and medicinal plants, related to betulinic acid. It is relatively non-toxic, antitumor, and hepatoprotective, as well as exhibiting antiviral properties. Learn More