2-O-Acetyl-20-hydroxyecdysone

Catalog No.: A78275
Ecdysterones
2-O-Acetyl-20-hydroxyecdysone is an ecdysteroid that targets various biological pathways associated with insect and plant physiology. This compound has demonstrated efficacy in inhibiting amyloid-β42 (Aβ42)-induced cytotoxicity, potentially reducing the formation of neurotoxic Aβ oligomers by promoting their transformation into less harmful fibrils. Its biological activity suggests applications in research related to neurodegenerative diseases and the modulation of protein misfolding.
Grouped product items
Size Price Stock Qty
1mg
$50.00
In stock
5mg
$160.00
In stock
10mg
$290.00
In stock
25mg
$485.00
In stock
50mg
$675.00
In stock
100mg
$870.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description2-O-Acetyl-20-hydroxyecdysone is an ecdysteroid that targets various biological pathways associated with insect and plant physiology. This compound has demonstrated efficacy in inhibiting amyloid-β42 (Aβ42)-induced cytotoxicity, potentially reducing the formation of neurotoxic Aβ oligomers by promoting their transformation into less harmful fibrils. Its biological activity suggests applications in research related to neurodegenerative diseases and the modulation of protein misfolding.
Product Information
Catalog NumA78275
FormulaC29H46O8
Molecular Weight522.67
CAS Number19536-25-5
SMILESC[C@@]12[C@@](C(C=C3[C@]2([H])CC[C@@]4(C)[C@@]3(O)CC[C@]4([H])[C@](O)(C)[C@H](O)CCC(O)(C)C)=O)([H])C[C@@H](O)[C@@H](OC(C)=O)C1
Synonyms20-Hydroxyeedysone 2-acetate
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