2002-H20

Catalog No.: A78419
Amyloid-β
2002-H20 is an inhibitor of amyloid-β (Aβ42) that functions by binding to the peptide to reduce its cytotoxic effects associated with Alzheimer's disease. This compound promotes fibril formation and may enhance Aβ aggregation, thereby protecting cells from Aβ-induced toxicity. 2002-H20 is a valuable tool for screening compounds that mitigate Aβ toxicity and holds potential as an inhibitory lead in Alzheimer's research.
Grouped product items
Size Price Stock Qty
5mg
$245.00
In stock
25mg
$640.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description2002-H20 is an inhibitor of amyloid-β (Aβ42) that functions by binding to the peptide to reduce its cytotoxic effects associated with Alzheimer's disease. This compound promotes fibril formation and may enhance Aβ aggregation, thereby protecting cells from Aβ-induced toxicity. 2002-H20 is a valuable tool for screening compounds that mitigate Aβ toxicity and holds potential as an inhibitory lead in Alzheimer's research.
Product Information
Catalog NumA78419
FormulaC20H15N3O3
Molecular Weight345.35
CAS Number351520-91-7
SMILESO=C(C1=CC=C(C=C1)N)NC2=CC=C(C(C3=NC4=CC=CC=C4O3)=C2)O
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