3-(1-Oxo-5-(3,9-diazaspiro[5.5]undecan-3-yl)isoindolin-2-yl)piperidine-2,6-dione is an E3 ligase ligand-linker conjugate designed for targeted protein degradation applications. This compound incorporates a CRBN-based ligand, enabling the synthesis of PROTAC (Proteolysis Targeting Chimeras) for selective protein modulation. It serves as a critical tool in chemical biology for studying protein function and therapeutic interventions in various diseases.
3-(1-Oxo-5-(3,9-diazaspiro[5.5]undecan-3-yl)isoindolin-2-yl)piperidine-2,6-dione is an E3 ligase ligand-linker conjugate designed for targeted protein degradation applications. This compound incorporates a CRBN-based ligand, enabling the synthesis of PROTAC (Proteolysis Targeting Chimeras) for selective protein modulation. It serves as a critical tool in chemical biology for studying protein function and therapeutic interventions in various diseases.
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