3-Chloro-5-hydroxybenzoic acid

Catalog No.: A60899
GPR81 Agonist
3-Chloro-5-hydroxybenzoic acid is a selective agonist of the lactate receptor GPR81, with an EC50 of 16 μM for human GPR81. This compound demonstrates significant biological activity, promoting lipolysis in a murine obesity model. It serves as a valuable tool for research focused on metabolic regulation and obesity-related pathways.
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Size Price Stock Qty
25mg
$20.00
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50mg
$30.00
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100mg
$35.00
In stock
200mg
$50.00
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description3-Chloro-5-hydroxybenzoic acid is a selective agonist of the lactate receptor GPR81, with an EC50 of 16 μM for human GPR81. This compound demonstrates significant biological activity, promoting lipolysis in a murine obesity model. It serves as a valuable tool for research focused on metabolic regulation and obesity-related pathways.
Product Information
Catalog NumA60899
FormulaC7H5ClO3
Molecular Weight172.57
CAS Number53984-36-4
SMILESClC1=CC(O)=CC(C(O)=O)=C1
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