3-Methyl-L-tyrosine

Catalog No.: A46256
Derivative of L-Tyrosine
3-Methyl-L-tyrosine is a derivative of L-Tyrosine that features a methyl group at the third position of the aromatic ring. This compound acts as a substrate for the protein tyrosine kinase Csk, demonstrating a catalytic efficiency (kcat/Km) of 38% relative to L-Tyrosine, indicating its role in modulating the enzymatic processing of Gsk. Research applications of 3-Methyl-L-tyrosine include studying the molecular recognition mechanisms of Gsk's substrates, which is essential for the design of specific inhibitors targeting Gsk in various therapeutic areas.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
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Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
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Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
Description3-Methyl-L-tyrosine is a derivative of L-Tyrosine that features a methyl group at the third position of the aromatic ring. This compound acts as a substrate for the protein tyrosine kinase Csk, demonstrating a catalytic efficiency (kcat/Km) of 38% relative to L-Tyrosine, indicating its role in modulating the enzymatic processing of Gsk. Research applications of 3-Methyl-L-tyrosine include studying the molecular recognition mechanisms of Gsk's substrates, which is essential for the design of specific inhibitors targeting Gsk in various therapeutic areas.
Product Information
Catalog NumA46256
FormulaC10H13NO3
Molecular Weight195.22
CAS Number17028-03-4
SMILESCC1=CC(=CC=C1O)C[C@@H](C(=O)O)N
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