(3S,5R)-Fluvastatin-d6 sodium is a deuterium-labeled derivative of the HMG-CoA reductase inhibitor, (3S,5R)-Fluvastatin. This compound exhibits a potent inhibitory activity with an IC50 of 8 nM, making it valuable for studying cholesterol biosynthesis. In addition to its role in lipid regulation, Fluvastatin has been shown to protect vascular smooth muscle cells from oxidative stress via the Nrf2-dependent antioxidant pathway, offering insights for cardiovascular research applications.
(3S,5R)-Fluvastatin-d6 sodium is a deuterium-labeled derivative of the HMG-CoA reductase inhibitor, (3S,5R)-Fluvastatin. This compound exhibits a potent inhibitory activity with an IC50 of 8 nM, making it valuable for studying cholesterol biosynthesis. In addition to its role in lipid regulation, Fluvastatin has been shown to protect vascular smooth muscle cells from oxidative stress via the Nrf2-dependent antioxidant pathway, offering insights for cardiovascular research applications.
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