4-Chloro-2-(trifluoroacetyl)aniline

Catalog No.: A85381
PXR Ligand
4-Chloro-2-(trifluoroacetyl)aniline is a potent ligand for the Pregnane X receptor (PXR). This compound is notable for its ability to induce Cyp3a11 mRNA expression, making it a valuable tool in studies of PXR-mediated drug metabolism and detoxification pathways. Its research applications are particularly relevant in pharmacology and toxicology, where understanding PXR activation can inform drug interactions and therapeutic efficacy.
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Size Price Stock Qty
100mg
$30.00
In stock
250mg
$60.00
In stock
500mg
$100.00
In stock
1g
$155.00
In stock
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description4-Chloro-2-(trifluoroacetyl)aniline is a potent ligand for the Pregnane X receptor (PXR). This compound is notable for its ability to induce Cyp3a11 mRNA expression, making it a valuable tool in studies of PXR-mediated drug metabolism and detoxification pathways. Its research applications are particularly relevant in pharmacology and toxicology, where understanding PXR activation can inform drug interactions and therapeutic efficacy.
Product Information
Catalog NumA85381
FormulaC8H5ClF3NO
Molecular Weight223.58
CAS Number154598-53-5
SMILESO=C(C1=CC(Cl)=CC=C1N)C(F)(F)F
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