4'-Ethynyl-2'-deoxyadenosine

Catalog No.: A18513

nucleoside reverse transcriptase (RT) inhibitor

4'-Ethynyl-2'-deoxyadenosine

4'-Ethynyl-2'-deoxyadenosine Chemical Structure

CAS NO. 306305-07-7

4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity.

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5 mg

Regular Price: $350.00

Special Price $280.00

10 mg

Regular Price: $650.00

Special Price $520.00

50 mg

Regular Price: $2,000.00

Special Price $1,600.00

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Biological Activity

4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36.33 mL 181.65 mL 363.29 mL
0.5 mM 7.27 mL 36.33 mL 72.66 mL
1 mM 3.63 mL 18.16 mL 36.33 mL
5 mM 0.73 mL 3.63 mL 7.27 mL

*The above data is based on the productmolecular weight 275.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18513
Actions Inhibitor
CAS No. 306305-07-7
Formula C12H13N5O3
M. Wt 275.26
Purity >98%
Synonyms 4'-E-dA, 4-E-dA
SMILES OC[[email protected]]1(C#C)[[email protected]](C[[email protected]](N2C=NC3=C(N=CN=C32)N)O1)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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