4'-Ethynyl-2'-deoxyadenosine

Catalog No.: A18513
nucleoside reverse transcriptase (RT) inhibitor
4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity.
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Product Name Price Stock Qty
4'-Ethynyl-2'-deoxyadenosine 5mg
$350.00
In stock
4'-Ethynyl-2'-deoxyadenosine 10mg
$650.00
In stock
4'-Ethynyl-2'-deoxyadenosine 50mg
$2,000.00
In stock
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Biological Activity
Discription 4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity.
Targets
Target Value
Product Information
Catalog Num A18513
Formula C12H13N5O3
Molecular Weight 275.26
CAS Number 306305-07-7
SMILES OC[C@]1(C#C)[C@H](C[C@H](N2C=NC3=C(N=CN=C32)N)O1)O
Synonyms 4'-E-dA, 4-E-dA
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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