4-Methylhistamine hydrochloride is a highly selective agonist for the histamine H4 receptor (H4R), exhibiting a Ki value of 50 nM and over 100-fold selectivity compared to other histamine receptor subtypes. With a pEC50 of 7.4, it effectively activates H4R, making it a valuable tool for research in cancer, inflammation, and immunology. Applications include studies related to lung cancer and skin inflammatory conditions, providing insights into H4R-mediated pathways in these areas.
4-Methylhistamine hydrochloride is a highly selective agonist for the histamine H4 receptor (H4R), exhibiting a Ki value of 50 nM and over 100-fold selectivity compared to other histamine receptor subtypes. With a pEC50 of 7.4, it effectively activates H4R, making it a valuable tool for research in cancer, inflammation, and immunology. Applications include studies related to lung cancer and skin inflammatory conditions, providing insights into H4R-mediated pathways in these areas.
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