4-Methylhistamine is a potent and selective agonist of the histamine 4 receptor (H4R), exhibiting a Ki of 50 nM and greater than 100-fold selectivity for hH4R relative to other histamine receptor subtypes. It effectively activates hH4R with a pEC50 of 7.4. This compound is valuable in research related to cancer, inflammation, and immunology, particularly in models of lung cancer and skin inflammation.
4-Methylhistamine is a potent and selective agonist of the histamine 4 receptor (H4R), exhibiting a Ki of 50 nM and greater than 100-fold selectivity for hH4R relative to other histamine receptor subtypes. It effectively activates hH4R with a pEC50 of 7.4. This compound is valuable in research related to cancer, inflammation, and immunology, particularly in models of lung cancer and skin inflammation.
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