4-Phenyl-1H-1,2,3-triazole

Catalog No.: A75724
IDO1 Inhibitor
4-Phenyl-1H-1,2,3-triazole is a potent inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with an IC50 value of 60 μM. This compound plays a crucial role in cancer research by modulating immune responses and inhibiting tumor-induced immune tolerance. Its ability to interfere with the kynurenine pathway makes it a valuable tool for studying tumor microenvironments and exploring new therapeutic strategies in oncology.
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Size Price Stock Qty
100mg
$30.00
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250mg
$45.00
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description4-Phenyl-1H-1,2,3-triazole is a potent inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with an IC50 value of 60 μM. This compound plays a crucial role in cancer research by modulating immune responses and inhibiting tumor-induced immune tolerance. Its ability to interfere with the kynurenine pathway makes it a valuable tool for studying tumor microenvironments and exploring new therapeutic strategies in oncology.
Product Information
Catalog NumA75724
FormulaC8H7N3
Molecular Weight145.16
CAS Number1680-44-0
SMILESC1(C2=CC=CC=C2)=CN=NN1
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