5,5′-(1,3-Propanediyl)bis-1,3,4-oxadiazole-2(3H)-thione is identified as a phosphodiesterase (PDE) inhibitor, specifically targeting both snake venom and human recombinant PDE 1 with IC50 values of 429 μM and 467 μM, respectively. Additionally, it exhibits weak inhibition of mushroom tyrosinase, with a calculated Ki of 1.9 μM. This compound can be utilized in biochemical research related to enzyme inhibition and potential pharmacological applications concerning PDE activity.
5,5′-(1,3-Propanediyl)bis-1,3,4-oxadiazole-2(3H)-thione is identified as a phosphodiesterase (PDE) inhibitor, specifically targeting both snake venom and human recombinant PDE 1 with IC50 values of 429 μM and 467 μM, respectively. Additionally, it exhibits weak inhibition of mushroom tyrosinase, with a calculated Ki of 1.9 μM. This compound can be utilized in biochemical research related to enzyme inhibition and potential pharmacological applications concerning PDE activity.
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