5,7-Dichloropyrazolo[1,5-a]pyrimidine is a potent inhibitor of phosphodiesterase 10A (PDE10A) with a Ki value of 24 μM. This compound plays a crucial role as an intermediate in the synthesis of 5,7-disubstituted pyrazolo[1,5-a]pyrimidine derivatives, which are investigated for their potential activity as non-nucleoside reverse transcriptase inhibitors against HIV-1. Additionally, 5,7-Dichloropyrazolo[1,5-a]pyrimidine is utilized in research relating to schizophrenia and related neuropsychiatric disorders.
5,7-Dichloropyrazolo[1,5-a]pyrimidine is a potent inhibitor of phosphodiesterase 10A (PDE10A) with a Ki value of 24 μM. This compound plays a crucial role as an intermediate in the synthesis of 5,7-disubstituted pyrazolo[1,5-a]pyrimidine derivatives, which are investigated for their potential activity as non-nucleoside reverse transcriptase inhibitors against HIV-1. Additionally, 5,7-Dichloropyrazolo[1,5-a]pyrimidine is utilized in research relating to schizophrenia and related neuropsychiatric disorders.
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