(5S,6R)-DiHETE is an enantiomer of the (5,6)-DiHETE family, primarily targeting leukotriene D4 receptors (LTD4). It exhibits significant biological activity by inducing contraction in isolated guinea pig ileum, with an EC50 value of 1.3 μM. This action can be effectively inhibited by LTD4 receptor antagonists, making (5S,6R)-DiHETE an important reagent for research applications focused on leukotriene signaling and gastrointestinal motility studies.
(5S,6R)-DiHETE is an enantiomer of the (5,6)-DiHETE family, primarily targeting leukotriene D4 receptors (LTD4). It exhibits significant biological activity by inducing contraction in isolated guinea pig ileum, with an EC50 value of 1.3 μM. This action can be effectively inhibited by LTD4 receptor antagonists, making (5S,6R)-DiHETE an important reagent for research applications focused on leukotriene signaling and gastrointestinal motility studies.
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