(5S,6R)-DiHETEs is the isomer of (5S,6R)-DiHETE, targeting leukotriene receptors, particularly LTD4 receptors. It demonstrates significant biological activity by inducing contraction in guinea pig isolated ileum, with an EC50 value of 1.3 μM. This action can be effectively inhibited by LTD4 receptor antagonists, making (5S,6R)-DiHETEs valuable for research in inflammatory response and receptor signaling pathways.
(5S,6R)-DiHETEs is the isomer of (5S,6R)-DiHETE, targeting leukotriene receptors, particularly LTD4 receptors. It demonstrates significant biological activity by inducing contraction in guinea pig isolated ileum, with an EC50 value of 1.3 μM. This action can be effectively inhibited by LTD4 receptor antagonists, making (5S,6R)-DiHETEs valuable for research in inflammatory response and receptor signaling pathways.
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