7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA) functions primarily as a phospholipase A2 (PLA2) inhibitor, exhibiting selective inhibition against both P388D1 cell PLA2 (IC50 = 16 µM) and snake venom PLA2 (IC50 = 14 µM). As a non-metabolizable analog of arachidonic acid, DEDA serves as a valuable tool in biochemical studies related to PLA2 activity. Its unique properties make it suitable for researching inflammatory processes and signal transduction pathways modulated by phospholipid metabolism.
7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA) functions primarily as a phospholipase A2 (PLA2) inhibitor, exhibiting selective inhibition against both P388D1 cell PLA2 (IC50 = 16 µM) and snake venom PLA2 (IC50 = 14 µM). As a non-metabolizable analog of arachidonic acid, DEDA serves as a valuable tool in biochemical studies related to PLA2 activity. Its unique properties make it suitable for researching inflammatory processes and signal transduction pathways modulated by phospholipid metabolism.
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