8-Azaadenine is a potent inhibitor of xanthine oxidase, exhibiting an IC50 value of 0.54 μM and a Ki of 0.66 μM. This compound can be synthesized through the metabolism of 8-Azaadenosine and is capable of integrating into polynucleotide chains alongside 8-Azaguanine, thereby influencing purine metabolism. 8-Azaadenine serves as a valuable tool in cancer research, enabling investigations into therapeutic strategies targeting purine biosynthesis pathways.
8-Azaadenine is a potent inhibitor of xanthine oxidase, exhibiting an IC50 value of 0.54 μM and a Ki of 0.66 μM. This compound can be synthesized through the metabolism of 8-Azaadenosine and is capable of integrating into polynucleotide chains alongside 8-Azaguanine, thereby influencing purine metabolism. 8-Azaadenine serves as a valuable tool in cancer research, enabling investigations into therapeutic strategies targeting purine biosynthesis pathways.
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